Talk with your doctor about the best options for treating your condition. They can help you decide whether the possible benefits for your condition outweigh your risks for serious side effects. Take calcium and vitamin D as your doctor tells you to help prevent low blood calcium. Heres some information on pregnancy, breastfeeding, and Prolia use. Prolia is a prescription medicine used to treat osteoporosis in women after menopause who are at high risk for fracture Your doctor can also advise you on symptoms of low calcium to look for. If youre concerned about side effects with Prolia, talk with your doctor. Vertigo (dizziness) was reported in some people who received Prolia for osteoporosis, but this was a less common side effect. These factors include what your insurance plan covers. As you age, your BMD is reduced, and this may increase your risk for osteoporosis. 1 shot every 6 months could mean fewer doses. Yes, if recommended by your doctor, you can stop taking Prolia. They may help you identify other possible causes or suggest ways to help manage hair loss. Prolia and Xgeva both contain the active drug denosumab, but they are not approved to treat all of the same conditions. Prolia can also cause bones to not form correctly and reduced growth in a fetus. See additional information. Prolia (denosumab) injection, for subcutaneous use. Prolia and Forteo are both used to treat osteoporosis. What should I know about Prolia vs. Zometa? Prolia is meant to be used in combination with calcium and vitamin D supplements. And you should continue using birth control for at least 5 months after stopping Prolia. WebNow that Im taking Prolia, do I still need calcium and vitamin D? While youre receiving Prolia treatment, your doctor will monitor your cholesterol levels with regular blood tests. It is based on denosumab and calcium (the active ingredients of Prolia and Calcium, respectively), and Prolia and Calcium (the brand names). Drug interactions are reported among people who take Prolia and Calcium. * Symptoms can include: flushing (temporary warmth, redness, or deepening of skin color), swelling under your skin, typically in your lips, eyelids, feet, or hands, swelling of your mouth, tongue, or throat, which can make it hard to breathe. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. Do any of yall know? If you have jaw pain or other mouth problems while youre using Prolia, tell your doctor or dentist. If youd like to learn more about Prolia, talk with your doctor or pharmacist. Prolia also carries a warning about hypocalcemia, which is a low level of 2,4. Follow your doctor's instructions about any restrictions on food, beverages, or activity. Prolia injection is a brand of denosumab, which treats osteoporosis. Side effects are possible with Prolia use, but in most cases they go away after a while. What Health Changes Should You Expect Postmenopause? So, if you want to stop taking Prolia, talk with your doctor. Now i am worried that i've been taking K2 which also takes calcium from the blood to the bones. You may wonder how Prolia compares to the medication Zometa. AlgaeCal Plus However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional. Studies of Prolia didnt report weight gain as a side effect of the drug. What do I need to be aware of if I need a tooth extraction while Im using Prolia? For women with osteoporosis after menopause at high risk for fracture. This is not a complete list of warnings for Prolia. To learn how Prolia and Tymlos are alike and different, see this comparison. You should not receive Prolia if you are allergic to denosumab, or if you have: low levels of calcium in your blood (hypocalcemia); or. Prolia Prolia has active ingredients of denosumab. Instead, it belongs to a different group of medications called biologics. Talk with your doctor about your health history and discuss your risks with Prolia treatment. This may include acetaminophen (Tylenol), naproxen (Aleve), or ibuprofen (Advil, Motrin). Xgeva is another brand of denosumab that treats high calcium levels caused by cancer and prevents bone breaks. These side effects may include: Its not known what percentage of people in clinical trials developed dental or jaw-related side effects. Coming to a Cleveland Clinic location?Hillcrest Cancer Center check-in changesCole Eye entrance closingVisitation and COVID-19 information, Notice of Intelligent Business Solutions data eventLearn more. If you are a healthcare professional, click "I Agree" to continue. What should I know about Prolia vs. Tymlos? With bone loss, your body loses old bone tissue faster than it makes new bone tissue. Prolia isnt known to cause any harmful interactions with alcohol. Muscle pain often contributes to back pain, one of the most common side effects reported in clinical trials of Prolia. Some items may interact with your medicine. Constipation was also reported as a side effect in females using Prolia for osteoporosis. So, dont be afraid to ask questions or offer feedback on your treatment. If you develop a side effect while taking Prolia and want to tell the FDA about it, visit MedWatch. Other conditions associated with osteonecrosis of the jaw include blood clotting disorders, anemia (low red blood cells), and a pre-existing dental problem. Examples of conditions Prolia is used off-label to treat include: Prolia is one option available to treat osteoporosis and reduce bone loss in people with a high risk for bone fracture. WebYou should take calcium and vitamin D as your doctor tells you to while you receive Your risk may also be higher if you: Stopping Prolia treatment can also increase your risk for bone fractures. What osteoporosis medications are there, and what side effects do they have? Your doctor can also help you decide if the benefits of Prolia treatment outweigh your risks of side effects. The conditions and factors to consider include: Upcoming dental procedures. Personalize this study to your gender and age, Arthrotec and Alanine Aminotransferase Increased, Capecitabine and Lumigan drug interaction, Cyramza and Gastrointestinal Stoma Necrosis, Simponi Aria and Pennsaid drug interaction, Docetaxel and Infection In An Immunocompromised Host, Ketorolac Tromethamine and Bladder Obstruction, Roxicodone and Caspofungin Acetate drug interaction, Ginkgo and Nitrofurantoin drug interaction. All rights reserved. The drug attaches to the RANK protein and helps prevent osteoclasts from breaking down bone. A few examples of bisphosphonates include: If youd like to know more about using a bisphosphonate for your condition, talk with your doctor. Check with your doctor if you have more questions about these drugs. It strengthens your bones by stopping certain bone cells called osteoclasts from breaking down your bones. Please know that the sponsors of this site are not responsible for content on the site you are about to enter. It is often used in osteoporosis. Like Helpful Hug REPLY 1 reply Mamie | @mamie | Oct And be sure to let your doctor know about all the medications youre currently taking. But theyre each effective in treating osteoporosis and preventing bone loss. Do not become pregnant while taking this medicine or for 5 months after stopping it. Your doctor can provide more information to you about the benefits and risks of using Prolia for your condition. Prolia and Evenity are both biologic medications, but Prolia contains the active drug denosumab, while Evenity contains the active drug romosozumab-aqqg. The risk is highest in people with cancer, blood cell disorders, pre-existing dental problems, or people treated with steroids, chemotherapy, or radiation. Some reports may have incomplete information. Find out which foods can help. This makes your bones weak and increases your risk for bone fractures or breaks. Prolia isnt approved to treat osteopenia or arthritis. Its recommended that you take 400 international units of vitamin D and 1,000 milligrams (mg) of calcium with Prolia. Side effects that you should report to your doctor or health care professional as soon as possible: Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome): This list may not describe all possible side effects. Copyright 1996-2023 Cerner Multum, Inc. Do not stop using this medicine without first talking to your doctor. Youll likely have questions about your condition and treatment choices. To learn more about this side effect, see Side effect specifics below. Is the ketogenic diet right for autoimmune conditions? Here are some frequently asked questions about the drugs side effects and their answers. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Prolia 60 mg/1 mL in a single-dose prefilled syringe (medicine). Doctors sometimes prescribe Prolia to treat osteoporosis and bone thinning. This medicine is only given in a clinic, doctor's office, or other health care setting and will not be stored at home. As mentioned above, Prolia contains the active drug denosumab. Our website services, content, and products are for informational purposes only. High cholesterol levels can be a side effect of Prolia. Your doctor can give you more information about the risks and benefits and how Reclast compares with Prolia. (Biosimilars are like generic drugs. People need calcium for bone health and other functions. (Biologic medications are made from living organisms.). Sciatica was a less common side effect in females* who received Prolia for osteoporosis after menopause. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. For example, an over-the-counter pain reliever can often ease mild pain such as joint or muscle pain, or headache. Call your doctor for medical advice about side effects. * Approximation only. Calcium has active ingredients of calcium. (A placebo is a treatment with no active drug.). If you have low calcium levels, you should not take Prolia. (To learn more, see the Side effect specifics section above.). They have some similar uses and side effects, but they also have some differences. Store in the original container away from heat and light. Prolia side effects: What you should know - Medical Advertising on our site helps support our mission. (2022). Prolia (Injection) Uses, Dosage & Side Effects - Drugs.com It is not known if the use of Prolia over a long period of time may cause slow healing of broken bones. If your pain becomes severe, your doctor may recommend other treatment options to replace Prolia. The absence of warnings or other information for a given drug does not indicate that the drug or drug combination is safe, effective, or appropriate for all patients or all specific uses. In this article well discuss the uses, side effects, safety precautions, and other important information about Prolia. Prolia is usually given once every 6 months. If youre concerned about unexplained weight gain while using Prolia, talk with your doctor. Talk with your doctor about which other treatments are better choices for you. Ask your doctor about the pros and cons of using Prolia. If your Prolia treatment is stopped, talk to your doctor about other medicine that Symptoms of a mild allergic reaction can include: A more severe allergic reaction is rare but possible. You should always consult your doctor or another healthcare professional before taking any medication. (Vitamin D helps your body absorb calcium.) Forteo is given as a self-injection once daily. Based on your dental history, your doctor can discuss with you the risks of using Prolia. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. They include bone pain, back pain, and a higher risk of certain infections. A biologic drug is made from parts of living organisms. This includes proper brushing, flossing, mouthwash use, and regular professional dental cleanings. Keep in mind that side effects of a drug can depend on: Additionally, you may experience different side effects from those listed below based on the condition youre treating with Prolia. What's the difference between Prolia and Reclast? Your side effects from Prolia may also vary depending on your gender. So your healthcare provider will likely ask you to take calcium and vitamin D supplements if youre not taking them already. Common side effects of this osteoporosis treatment injection include muscle, joint, and back pain. They can help answer any questions you have about side effects from taking the drug. (Chlorhexidine helps kill germs in your mouth.). They include: not getting enough calcium and vitamin D smoking drinking too much alcohol using certain medications, such as corticosteroids and anticonvulsants not getting enough weight-bearing exercise (at least 30 minutes on most days). NOTE: This sheet is a summary. Nausea can sometimes be a symptom of severe constipation. If you develop serious side effects while taking Prolia, call your doctor right away. Kidney problems. Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once. Drug class: miscellaneous bone resorption inhibitors. However, drinking too much alcohol may raise your risk of falling. Take only the amount of calcium and vitamin D that your doctor has prescribed. You should receive your missed injection as soon as possible. The list below may not include all possible serious side effects of the drug. (Biosimilars are like generic drugs. Be sure to talk with your doctor about your health history before you take Prolia.

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